You may qualify to join the study if you:*

  • Are 18 through 65 years of age
  • Have sensorimotor complete or incomplete, traumatic, non-penetrating SCI (ASIA Impairment Scale A or B)
  • Have a neurological level of injury from C4 to T10
  • Able to participate in an elective surgical procedure to inject LCTOPC1 within 21-42 days (subacute) or 1-5 years (chronic) following SCI

Please contact the nearest participating clinical site to learn if you qualify to participate in the study.

Study Design & Duration

DOSED is an open label, multi-center safety study meaning that all eligible, consented participants will receive LCTOPC1. LCTOPC1 is delivered directly into the spinal cord in a single surgical procedure.  The device used to deliver LCTOPC1 is being evaluated for safety. Participants will be followed for 10 years with more frequent assessments in the first year after the injection procedure including physical exams, blood tests and MRIs.

*This is only a selection of the inclusion and exclusion criteria that patients must meet in order to take part in the investigational study and does not guarantee participation. More detailed information may be found at clinicaltrials.gov

Learn more about how to find a study site and frequently asked questions about DOSED

Contact a
Study Site

Frequently
Asked Questions

© Copyright 2026 Lineage Cell Therapeutics, Inc.
This study is sponsored by Lineage Cell Therapeutics, Inc.